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If all the enzymes, intermediates and cofactors of the citric acid cycle as well as an excess of the starting substrate acetyl-CoA are present and functional in an organelle free solution at the appropriate pH, which of the following factors of the citric acid cycle would prove to be rate limiting?

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If all the enzymes, intermediates and cofactors of the citric acid cycle as well as an excess of the starting substrate acetyl-CoA are present and functional in an organelle free solution at the appropriate pH, which of the following factors of the citric acid cycle would prove to be rate limiting?






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