The use of Markov models in gene finding exploits the fact that oligonucleotide distributions in the coding regions are different from those for the noncoding regions.

Gene and promoter prediction is a crucial research area in bioinformatics. Accurate prediction of promoters is important for understanding gene function and regulation, and for interpreting gene expression patterns.

Topics include: Categories of Gene Prediction Programs, Gene Prediction in Prokaryotes, & Gene Prediction in Eukaryotes.