1. Two species that have recently diverged from a common ancestor might be expected to have a ________ set of genes and ________ chromosomes with these genes positioned along the chromosomes in the same order.

2. Which of the given statement is incorrect?

3. In cluster analysis of microarray data– If X_i is the log odds value for gene X at time i, then for two genes X and Y and N observations, a similarity score is calculated. S(X,Y) is also known as the Pearson correlation coefficent. X_offset and Y_offset can be the mean of the observations on X or Y, respectively, in which case is the standard deviation, or else X_offset and Y_offset can be set to zero when a reference state is used. Which of the following best represents it?

4. When two proteins share a considerable degree of sequence identity throughout the sequence alignment, they are least likely to share the same function.

5. A genome database may also be interfaced with other types of data, such as clinical data.

6. Other types of evidence for a relationship between two genes are also given that are not dependent in sequence similarity. Which of the following is a wrong statement?

7. In Self-organizing maps a choice is made of a number of clusters by which to organize the data.

8. Other functional classification schemes for genes include a broader category for genes involved in the same biological process, e.g., a three-group scheme for energy-related, information-related, and communication-related genes has also been used.

9. SVMs (Support vector machines) are a binary classification method to discriminate one set of data points from another.

10. Which of the following is not a characteristic of Fuzzy or approximate matches in regular expression?

11. Which of the given statement is incorrect regarding MAGPIE?

12. Emotif uses which databases for alignment of sequences?

13. Which of the following is not a characteristic of exact matches in regular expression?

14. Which of the given statement is incorrect?

15. Which of the given statements is incorrect about Microarray Analysis?

16. In case of functional genomics– Two general types of approaches are used—one in which a genetic construct is made that interferes with the expression of a particular gene (and sometimes a set of related genes) and a second in which a large number of random mutations are generated in a population of organisms.

17. In regular expressions, which of the following pair of pattern is wrongly matched with its significance?

18. The designation ECa.b.c.d conveys information. Which of the following is not one of it?

19. Which of the given statement is untrue about functional genomics?

20. In cluster analysis of microarray data– For n genes, the process is repeated ________ times until a single element remains.

21. In Reverse-genetics analysis of gene function– Even though a particular gene may be _____ ortholog of a gene of known function in another organism, that gene may be acquired by a _____ function.

22. The hierarchical clustering method generates a similarity score [S(X,Y)] for all gene combinations, places the scores in a matrix, joins those genes that have the highest score, and then continues to join progressively less similar pairs.

23. In regular expressions, which of the following pair of pattern is wrongly matched with its significance?

24. In SVMs (Support vector machines) Data points are log-transformed and normalized as in method A, where for N observations of a gene i, the log transform X_i of the expression level E_i and reference level R_i is?

25. Which of the given statement is incorrect about the observations made with regard to gene order?