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Bioinformatics Practice Test Questions: Genome Mapping, Assembly and Comparison
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Genome mapping, assembly, and comparison are related processes:
 

Genome mapping: A physical map is created using DNA fragments and markers to assemble larger DNA sections. DNA base locations can be identified from the overlapping sections of the fragments.
Genome assembly: The process of putting nucleotide sequences into the correct order.
Genome comparison: A comparison of general features of genomes, such as genome size, number of genes, and chromosome number
 

Topics include: Genome Mapping, Genome Sequencing, Genome Sequence Assembly, Genome Annotation, & Comparative Genomics.

Bioinformatics Practice Test Questions: Genome Mapping, Assembly and Comparison
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25 Questions

1. VecScreen is a primarily aimed for sequence assembly.
2. Which of the following is incorrect regarding GeneQuiz?
3. Which of the following is untrue about Gene Order Comparison?
4. Which of the following is incorrect?
5. The remote homology detection helps to shed light on the possible functions of the proteins that previously have no functional information at all.
6. Which of the following is untrue about base calling and assembly programs?
7. The shotgun approach _______ sequences clones from _____ of cloned DNA.
8. A way to discern lateral gene transfer is through phylogenetic analysis, referred to as an ‘among-genome’ approach, which can be used to discover __________
9. Which of the following is untrue about comparative genomics?
10. Which of the following is incorrect about Phred?
11. In medical applications, the ultimate goal of gene mapping is to disease genes.
12. In hierarchical genome sequencing approach, based on the results of _______ mapping _______of the BAC clones on a chromosome can be determined.
13. Conserved functional sites can be identified by profile and hidden Markov model–based motif and domain search tools such as SMART and InterPro.
14. The _____ resolution genome map is the genomic DNA sequence that can be considered as a type of ______ map describing a genome at the single base-pair level.
15. Which of the following is incorrect regarding gene annotation?
16. Physical maps are constructed by using a chromosome walking technique.
17. Which of the following is incorrect regarding gene ontology?
18. The hierarchical approach is ____ and _____ than the shotgun approach because it involves an initial clone-based physical mapping step.
19. Which of the following is incorrect about Phrap?
20. Which of the following is incorrect regarding Automated Genome Annotation?
21. Genetic linkage maps, also called genetic maps, identify the relative positions of genetic markers on a chromosome and are based on how frequent the markers are inherited together.
22. Which of the following is untrue about LAGAN?
23. Which of the following is untrue about Whole Genome Alignment?
24. Which of the following is incorrect regarding gene ontology?
25. The whole genome shotgun approach can produce a draft sequence very rapidly because it is based on the direct sequencing approach.

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