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Bioinformatics Practice Test Questions: Molecular Phylogenetics
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Molecular phylogeny is a relatively new scientific discipline that involves the comparative analysis of the nucleotide sequences of genes and the amino acid sequences and structural features of proteins from which evolutionary histories and relationships, and in some cases also functions, can be inferred.

Topics include: Phylogenetics Basics, Gene Phylogeny Versus Species Phylogeny, & Forms of Tree Representation.

Bioinformatics Practice Test Questions: Molecular Phylogenetics
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25 Questions

1. To obtain a species phylogeny, phylogenetic trees from a variety of gene families need to be constructed.
2. Which of the following is incorrect statement about Molecular Markers?
3. In many cases ______ sequences are preferable to ______ sequences because they are relatively ____ conserved.
4. Which of the following is an incorrect statement about Newick Format?
5. Which of the following is incorrect regarding the advantages of Molecular data for phylogenetics study?
6. For studying the evolution of ________ divergent groups of organisms, one may choose either ______ nucleotide sequences, such as ribosomal RNA or protein sequences.
7. Which of the following is incorrect regarding the terminologies of phylogenetics?
8. DNA sequences are sometimes more biased than protein sequences because of preferential codon usage in different organisms.
9. It can be computationally very demanding to find a true phylogenetic tree when the number of sequences is large.
10. In Jukes–Cantor Model to correct evolutionary distances, A formula for deriving evolutionary distances that include hidden changes is introduced by using a logarithmic function. It is ____
11. Which of the following is incorrect regarding the terminologies of phylogenetics?
12. The second step in phylogenetic analysis is to construct sequence alignment. This is probably the most critical step in the procedure because it establishes positional correspondence in evolution.
13. Molecular clock is an assumption by which molecular sequences evolve at varying rates.
14. Which of the following is incorrect statement about Choosing Substitution Models?
15. The number of rooted trees (NR) for n taxa is ______
16. Which of the following is incorrect statement about the Kimura model?
17. Evolution of a particular sequence _______ correlate with the evolutionary path of the species.
18. The species evolution is the ______ of evolution by _____ in a genome.
19. Because there is no indication of which node represents an ancestor, there is no direction of an evolutionary path in an unrooted tree.
20. Which of the following is an incorrect statement?
21. The descriptions of morphological traits are often _____ which are due to _____
22. Protein sequences can remain the same while the corresponding DNA sequences have more room for variation.
23. Building phylogenetic tree involves bifurcation and multifurcation.
24. Which of the following is incorrect regarding the terminologies of phylogenetics?
25. To use molecular data to reconstruct evolutionary history requires making a number of reasonable assumptions. Which of the following is incorrect about it?

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