Leucine zipper domains are a special type of coiled coils found in transcription regulatory proteins which contain two anti parallel α-helices held together by hydrophobic interactions of leucine residues.

Secondary structure prediction is a set of techniques in bioinformatics that aim to predict the secondary structures of proteins and nucleic acid sequences based only on knowledge of their primary structure.

Topic include: Protein Secondary Structure Prediction for Globular Proteins, Secondary Structure Prediction for Transmembrane Proteins, & Coiled Coil Prediction.