If the random sequences were prepared in a way that maintained the local base composition by producing them from overlapping fragments of sequence, the distribution of scores has a _______ standard deviation that is closer to the distribution of the natural sequences.

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In bioinformatics, sequence alignment is a way of arranging DNA, RNA, or protein sequences to identify regions of similarity. These similarities may be a result of functional, structural, or evolutionary relationships between the sequences. Topics include:  Protein Motifs and Domain Prediction, Motif and Domain Databases Using Regular Expressions, Motif and Domain Databases Using Statistical Models, Protein Family Databases, Global Sequence Alignment, Local Sequence Alignment, Motif Discovery in Unaligned Sequences, Dot Matrix Sequence Comparison, Dynamic Programming Algorithm for Sequence... Show more

If the random sequences were prepared in a way that maintained the local base composition by producing them from overlapping fragments of sequence, the distribution of scores has a _______ standard deviation that is closer to the distribution of the natural sequences.