In Fred Griffith's experiments, harmless R strain pneumococcus became lethal S strain pneumococcus as the result of which of the following? 1.horizontal gene transfer 2.transduction 3.conjugation 4.transformation 5.genetic recombination

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In Fred Griffith's experiments, harmless R strain pneumococcus became lethal S strain pneumococcus as the result of which of the following? 1.horizontal gene transfer 2.transduction 3.conjugation 4.transformation 5.genetic recombination