Which proteolytic enzyme was used in the experiments aimed at elucidating the mutation that causes sickle cell anemia?

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Gene expression is the process of using information from a gene to create a functional gene product. This product can then produce end products, such as proteins or non-coding RNA, which can affect a phenotype. Gene expression involves transcribing genes into mRNAs, and then translating the mRNAs into proteins. The central dogma of molecular biology describes the directional flow of information during the expression of a protein-coding gene. This flow goes from DNA to RNA to protein.  Gene expression is important because a specific protein can only be produced when its gene is turned on. It... Show more

Which proteolytic enzyme was used in the experiments aimed at elucidating the mutation that causes sickle cell anemia?