Fouling factor is obviously__________ for a new heat exchanger and __________ with time as the solid deposits build up on the heat exchanger surface.

Biochemical Engineering mainly deals with the design, construction, and advancement of unit processes that involve biological organisms (such as fermentation) or organic molecules (often enzymes) and has various applications in areas of interest such as biofuels, food, pharmaceuticals, biotechnology, and water treatment processes. (Source: Wikipedia)