Consider the following two reactions: (1) glutamate + NH4+ ↔ glutamine, for which ∆rG0 = 15.7 kJ/mol at 37oC; and (2) ATP ↔ ADP + Pi, for which ∆rG0 = -31.0 kJ/mol at 37oC. (In reaction (2), ATP denotes adenosine triphosphate, ADP denotes adenosine diphosphate, and Pi represents inorganic phosphate.) These two reactions can be coupled by an enzyme catalyst (glutamine synthetase), which leads to the following reaction: (3) glutamate + NH4+ + ATP ↔ glutamine + ADP + Pi. What is the equilibrium constant for reaction (3) at a temperature of 37oC?

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MCQs on thermodynamics in classical mechanics systems. Topics include the first, second, and third laws of thermodynamics, energy, work, enthalpy, and entropy, spontaneity, chemical potential, equilibrium, phase changes, and chemical kinetics.


Consider the following two reactions: (1) glutamate + NH<sub>4</sub><sup>+</sup> ↔ glutamine, for which ∆<sub>r</sub>G<sup>0</sup> = 15.7 kJ/mol at 37<sup>o</sup>C; and (2) ATP ↔ ADP + Pi, for which ∆<sub>r</sub>G<sup>0</sup> = -31.0 kJ/mol at 37<sup>o</sup>C. (In reaction (2), ATP denotes adenosine triphosphate, ADP denotes adenosine diphosphate, and Pi represents inorganic phosphate.) These two reactions can be coupled by an enzyme catalyst (glutamine synthetase), which leads to the following reaction: (3) glutamate + NH<sub>4</sub><sup>+</sup> + ATP ↔ glutamine + ADP + P<sub>i</sub>. What is the equilibrium constant for reaction (3) at a temperature of 37<sup>o</sup>C?





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