Over an extended period - carcinogens - such as chemicals found in tobacco smoke - polluted air and water - toxic wastes - and even the high ____ content of foods - may convert protooncogenes into oncogenes.

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1. Over an extended period - carcinogens - such as chemicals found in tobacco smoke - polluted air and water - toxic wastes - and even the high ____ content of foods - may convert protooncogenes into oncogenes.