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BIO301 Final Exam (Cell Biology)
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MCQs on the cell and its structures, including molecular compounds, structural features, and organelles including the nucleus, cytoskeleton, and extracellular matrix. Particular emphasis on transport mechanisms and membrane trafficking, cellular signaling, the cell cycle including mitosis and meiosis, and gene expression.
 

BIO301 Final Exam (Cell Biology)
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25 Questions

1. Rb is a protein that plays different roles during the cell cycle depending on its level of phosphorylation. In G0 phase, what would its state and its role be?
2. Which of the following is true of guanalyl cyclase receptors?
3. A molecule that is not membrane permeable binds to a membrane protein on the outside of a cell. This changes the conformation of the protein, causing the binding site to face the inside of the cell. The molecule is then released into the cell and the conformation of the binding site changes again so that it is outside the cell. This is a description of what type of transport(er)?
4. Epithelial cells that must control the movement of ions and molecules between adjacent cells most likely have what kind of junctions between them?
5. Suppose the Gα subunit of a G-protein-coupled receptor could not hydrolyze GTP. Which of the following represents the most direct effect this would have on the G-protein-coupled-receptor process?
6. A plant seed would need which of the following organelles for energy, as it converts fatty acids to carbohydrates?
7. You want to be able to observe a cell during specific points in mitosis. You expose the cell to a drug that prevents sister chromatids from separating. At which step of the mitotic cycle have you arrested the cell?
8. In mammals, a DNA damage signal will lead a cell to arrest the cell cycle. In what way will it accomplish this?
9. Identify the mitotic phase or cell behavior during which the following occurs in animal cells: chromosomes de-condense.
10. If you were an active organism (for example, an animal) and wanted to store energy efficiently, what type of molecule would be best suited for this purpose?
11. Suppose the concentration of GTP in a cell were dramatically reduced so that it was much less abundant than GDP. Which of the following represents the most direct effect this would have on the G-protein-coupled-receptor process?
12. During which phase of mitosis would you first be able to distinguish the difference between a cell undergoing closed vs. open mitosis?
13. Which of the following events occurs during the anaphase of meiosis I?
14. At which stage of the mitotic cycle would you be unable to observe tightly condensed chromosomes under the microscope?
15. Identify the stage of meiosis I prophase during which the following occurs: the spindle forms and nuclear envelope breaks down.
16. Some genes that are present in all cells are only active in certain cells or tissues. What is the best and most likely way through which this selective expression occurs?
17. In the extracellular matrix of tendon cells, you would expect to find:
18. Identify the type of receptor based on its description: one of the most common receptors in eukaryotic cells, they have seven membrane-spanning domains.
19. Which of the following occurs in bacterial cells during mitosis and cell division?
20. Which of the following statements is false?
21. If a biological reaction results in an increase in free energy (G), then:
22. Which of the following is an example of symport?
23. Identify the stage of meiosis I prophase during which Recombination occurs.
24. What property of actin assembly leads to its very high turnover in cells that is, causing it to rapidly assemble and disassemble?
25. In order for a cell to crawl, what must occur?