1. One the following is measured in amperometric titration

2. Choose the correct semi-rigid gel used for exculsion chromatography

3. Low dose aspirin acts as anti-platelet aggregating agent by which one of the following mechanisms? Find the correct answer.

4. Which one of the following drugs is 'Topoisomerase I inhibitor' ?

5. Which one of the following is an antifungal polyene macrolide antibiotics with seven conjugated double bond, an internal ester, a free carboxyl group and a glycoside side chain with primary amino group

6. Which one of the following is a Histamine H1 receptor antagonist?

7. Some statements about crystals are given below: [P] The crystal lattice is constructed from repeating units called unit cells. [Q] The external appearance of a crystal is described by crystal habits, such as needles, prisms, rosettes etc. [R] Polymorphism is the ability of a compound to crystallize as more than one distinct crystalline species with different internal lattice. [S] Hydrates are always more soluble than anhydrous form of the same drug Choose the corrected combination of statements about crystals.

8. Which of the following metals has no therapeutic use?

9. Which laxative acts by a detergent-like effect?

10. In the preparation of multilayer tablets one of the substances listed is used to Hydrophilic matrix coating

11. Following statements are given for local anaesthetic drug lidocaine: [P] It contains a xylidine moiety [Q] It can be used as antiarrhythmic agent on oral administration. [R] When administered along with adrenaline its toxicity is reduced and its effect is prolonged. [S] Chemically it is 2-diethylamino-2',6'-dimethylphenyl acetamide Choose the correct combination of statements.

12. The following drugs have significant drug interaction with digoxin, except ?

13. Cetirizine as an antihistaminic agent has a low sedative potential due to one of the following reasons. Identify that.

14. Which one of the following is the fastest acting inhalational agent ?

15. The hydrogen deficiency index is a measure of:

16. The following prescription is given to the pharmacist by the physician to dispense Rx Calciferol solution 0.3 Water to Q.S 5.0 ml send 25 ml Final dosage of this prescription will be

17. In amperometry, rotating platinum electrode (RPE) is used as indicating electrode. It has certain advantages as well as disadvantages. Read the following statements about the use of rotating platinum electrode in amperometry: [P] It causes large diffusion current due to rotation resulting in greater mass transfer [Q] It causes greatly reduced residual current due to lack of condenser effect [R] It has a low hydrogen over potential Choose the correct combination of statements.

18. Diclofenac tablet coated with cellulose acetate phthalate has been administered to a patient. Where do you except the drug to be released?

19. β-phenyl-N-alkyl piperidine moiety is largely responsible for activity in one of the following. Choose the correct one

20. The dip tube in an aerosol container is made from one of the following. Choose the correct one

21. Followings are some drug derivatives used to increase/ decrease the water solubility of the parent drugs: [P] Rolitetracycline [Q] Erythromycin lactobionate [R] Chloramphenicol succinate [S] Erythromycin stearate Choose the correct combination of statements.

22. The group of antibiotics which possess additional antiinflammatory and immunomodulatory activities is ?

23. What will be the approximate Tmax of a drug exhibiting Ka of 2 hr'1 and K of 0.2 hr-1?

24. There are some criteria which an ideal antacid should fulfill. Some of the criteria are given below: [P] The antacid should be absorbable orally and should buffer in the pH range of 4 - 6 [Q] The antacid should exert its effect rapidly and should not cause a large evolution of gas [R] The antacid should not be a laxative or should not cause constipation [S] The antacid should react with the gastric acid and should inhibit pepsin Choose the correct combination of criteria for an ideal antacid.

25. In polarography, when the limiting current is achieved, one of the following processes takes place. Choose that.