1. Aprotic polar solvents increase the rate of SN2 reactions manifold. Enhancement in the rate of such reactions is due to which one of the following effects?

2. The following statements are given: (P) Conformational isomers are interconvertible by rotation around a single bond while configurational isomers cannot be interconverted without breaking a bond. (Q) Configurational isomers could be optically active or optically inactive while conformational isomers are optically inactive. (R) Geometric isomers must have a double bond in their structures. (S) Geometric and optical isomers are the two distinct categories of configurational isomers. Choose the correct combination of statements.

3. Which condition does not apply as per Indian law while conducting single dose bioavailability study of an immediate release product?

4. Define Plasmapheresis. Choose the correct answer.

5. Which of the following isothems are produced when the heat of condensation of successive layers is more than the heat of adsorption of first layer?

6. Upon standing, sometimes gel system shrinks a bit and little liquid is pressed out. What is this phenomenon known as?

7. Which of the following statements is incorrect?

8. What for the baffles are provided in a shell and tube heat exchanger?

9. Which of the following species is being inactivated by the enzyme Dipeptidyl peptidase-4?

10. Two genetic types of Cannabis i.e., drug type and Hemp type are cultivated. (P) Drug type cannabis is rich in (-)A-transtetrahydrocannabinol. (Q) Hemp type cannabis is rich in cannabidiol (R) Drug type cannabis is rich in cannabidiol (S) Hemp type cannabis contains elongated bast fibres Which one of the given statements is correct?

11. What is the wavenumber equivalent of 400 nm wavelength?

12. Khellin is an active constituent of which one of the following plants?

13. What is chemotaxis?

14. If the distillation graph using McCabe Thiele method is parallel to X-axis, then the feed is which one of the following?

15. A drug whose solubility is 1 g/L in water, when given orally at a dose of 500 mg is absorbed upto 95% of the administered dose. The drug belongs to which class according to the BCS classification?

16. Which of the following routes of administration of drugs is associated with Phlebitis?

17. Each of the following option lists a phytoconstituent, its phytochemical grouping, pharmacological activity and corresponding semisynthetic analogue. Find a mismatching option.

18. Choose the correct statement for writing the sequence of amino acids in a polypeptide.

19. Each of the following options lists the name of the drug, its class, pharmacological action and plant source. Choose an option showing a wrong combination.

20. Which is not applicable to protein binding?

21. Iodine-131 as sodium iodide solution is used as a radiopharmaceutical for diagnostic and therapeutic purposes. Its usage is dependent on the release of the following emissions: (P) Alpha particles (Q) Positrons (R) Beta emission (S) Gamma radiation Choose the correct combination of statements:

22. Choose the correct sequence of Moisture VapourTransmission Rate in packaging materials.

23. Which microbe is used for validation of sterilization by filtration process?

24. A 64 year old woman with a history of Type II diabetes is diagnosed with heart failure. Which of the following would be a poor choice in controlling her diabetes?

25. Choose the correct pair of the neurodegenerative disorders from those given below.