A defective hexosaminidase A (HexA) needed for in metabolizing GM2 is responsible for ____. HexA is a ___ of αβ, which are encoded by the HEXA and HEXB genes, respectively.

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1. A defective hexosaminidase A (HexA) needed for in metabolizing GM2 is responsible for ____. HexA is a ___ of αβ, which are encoded by the HEXA and HEXB genes, respectively.