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A small fraction of PKU patients (1~3%) have normal PAH but are defective in genes that are needed for the synthesis or regeneration of ____, the cofactor of PAH. ____ is also the cofactor for two other enzymes, tyrosine hydroxylase and tryptophan hydroxylase, both of which synthesize monoamine neurotransmitters.

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1. A small fraction of PKU patients (1~3%) have normal PAH but are defective in genes that are needed for the synthesis or regeneration of ____, the cofactor of PAH. ____ is also the cofactor for two other enzymes, tyrosine hydroxylase and tryptophan hydroxylase, both of which synthesize monoamine neurotransmitters.





 
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