ATD Individuals with ___ genotype have only 10-15% of normal α1-AT activity and account for most cases of the disease. Individuals with ___ genotype have 50-60% of normal α1-AT activity and usually do not express disease symptoms. ___ compound heterozygotes have 30-35 % of normal α1-AT activity and may develop emphysema.

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1. ATD Individuals with ___ genotype have only 10-15% of normal α1-AT activity and account for most cases of the disease. Individuals with ___ genotype have 50-60% of normal α1-AT activity and usually do not express disease symptoms. ___ compound heterozygotes have 30-35 % of normal α1-AT activity and may develop emphysema.