Common in Africa, Mediterranean, and Asia. Deletion of one of the two α-globin genes in the α-cluster. 50% decrease in α-globin synthesis. No disease phenotype in heterozygote (αα/α-,silent carrier). Mild anemia in homozygotes (α-/α-), a.k.a. α-thalassemia-2 trait.

🎲 Try a Random Question  |  Total Questions in Quiz: 599  |  🧠 Study this quiz with Flashcards
This question is part of a full practice quiz:
Genetics Exam Practice Questions — practice the complete quiz, review flashcards, or try a random question.


1. Common in Africa, Mediterranean, and Asia. Deletion of one of the two α-globin genes in the α-cluster. 50% decrease in α-globin synthesis. No disease phenotype in heterozygote (αα/α-,silent carrier). Mild anemia in homozygotes (α-/α-), a.k.a. α-thalassemia-2 trait.