PKU mothers who are not on a low-phenylalanine diet have a markedly increased risk of ____ and giving birth to children with ____, mental retardation, and growth impairment, ____ of the genotypes of the children.

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1. PKU mothers who are not on a low-phenylalanine diet have a markedly increased risk of ____ and giving birth to children with ____, mental retardation, and growth impairment, ____ of the genotypes of the children.