Smoking accelerates the onset of emphysema in ATD patients. Tobacco smoke damages the lung, prompting the body to send more ____ to the lung for protection. More ____ release more ___, causing more severe lung damage.

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1. Smoking accelerates the onset of emphysema in ATD patients. Tobacco smoke damages the lung, prompting the body to send more ____ to the lung for protection. More ____ release more ___, causing more severe lung damage.