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The ___ allele (most commonly mutated) expresses a misfolded protein that aggregates in the endoplasmic reticulum (ER) of liver cells, causing damage to the liver in addition to the lung. The ___ allele (Glu264Val) expresses an unstable protein that is less effective.

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1. The ___ allele (most commonly mutated) expresses a misfolded protein that aggregates in the endoplasmic reticulum (ER) of liver cells, causing damage to the liver in addition to the lung. The ___ allele (Glu264Val) expresses an unstable protein that is less effective.





 
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