____: The disease is due to a CTG expansion in the 3’UTR of the DMPK gene, which encodes a protein kinase. Expanded CUG repeats in RNA lead to the novel property of excessive binding to a variety of RNA-binding proteins, (splicing regulators); thus, impairing RNA splicing of mRNAs for key proteins.

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1. ____: The disease is due to a CTG expansion in the 3’UTR of the DMPK gene, which encodes a protein kinase. Expanded CUG repeats in RNA lead to the novel property of excessive binding to a variety of RNA-binding proteins, (splicing regulators); thus, impairing RNA splicing of mRNAs for key proteins.