____: Zero β-globin synthesis so that no HbA is present. [Hb] is ~5% of normal level (of which 95% is αγ with 5% αδ), which is not enough for good survival.

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1. ____: Zero β-globin synthesis so that no HbA is present. [Hb] is ~5% of normal level (of which 95% is αγ with 5% αδ), which is not enough for good survival.