1. Mouse One has a defect that prevents T lymphocytes from maturing. Mouse Two has a defect that prevents complete thymus development. Neither mouse has mature T cells. What is one way to induce the development of mature T cells in Mouse One?

2. A major type of cancer therapy currently in development involves the use of tumor vaccines. What do these vaccines consist of?

3. Which of the following immunosuppressants would you use if a patient exhibited dangerously high levels of inflammation?

4. Which of the following is used to present self-antigen as a way to monitor proteins produced inside host cells?

5. The parasite that causes malaria enters red blood cells and is relatively undetected by T cells. Which of the following is a possible reason for its ability to avoid detection by T cells?

6. Complete the following sentence. Point mutations of the V regions of light- and heavy-chain genes occur at a dramatic rate, leading to the expression of variant B-cell receptors on B cells. This occurrence is known as:

7. You are fighting off a viral infection. Which of the following interactions will be used to successfully remove this invading virus?

8. A pathogen enters your blood. Assuming that your innate immune system is unable to eliminate it, where would your T cells be presented with this pathogen?

9. Point mutations of the V regions of light- and heavy-chain genes occur at a dramatic rate, leading to the expression of variant B-cell receptors on B cells. Is this occurrence an advantage or a disadvantage for B cells' function, and why?

10. Which of the following statements about B cell immunological memory is false?

11. When you get a cold, you might notice that you have swollen glands, lumps of swelling on either side of the base of your jaw. What immunological activity causes this?

12. Which complement-system pathway can provide amplification of the other two pathways?

13. Complete the following sentence. A friend of yours smells a flower and immediately starts sneezing. In order to annoy him, you immediately diagnose him with the correct immunological term for his condition, which is:

14. Tumor cells can evade the immune system in which of the following ways?

15. Which of the following statements about neutrophils is false?

16. The use of specific epitopes in protein-based vaccines is a current area of study. What is one problem with this approach?

17. Why is there no problem with the pregnancy of an Rh-negative mother carrying an Rh-positive child if the mother had never been exposed to Rh previously, when a second pregnancy with another Rh-positive child leads to a miscarriage?

18. A sample of an individual's immune-system cells shows normal levels of all cell types except dendritic cells: these are present in very low numbers. Which of the following best describes the effect, if any, that this will have on the individual's adaptive immune response?

19. Which of the following molecules is usually expressed only by antigen-presenting immune-system cells?

20. Which MHC class type do Antigen Presenting Cells express on their surface?

21. Which of the following is an example of passive immunization?

22. If you wanted to stop B-cell development in vitro, you would do which of the following?

23. A researcher finds that some of her mice lack appropriate B cell function; they seem unresponsive to antigens that should stimulate B cells. She discovers that although these mice produce healthy B cells and normal-looking receptors, those receptors are only present within B cells rather than on the B-cell surface. The researcher concludes that these cells are lacking which of the following?

24. Which complement-system pathway is initiated with the help of antibodies bound to the surface of a pathogen?

25. Which of the following types of immune-system cells respond immediately to bacterial infections and release chemokines and cytokines?