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Opioids Study Guide
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Opioids Study Guide
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25 Questions

1. Kappa receptor agonist example

2. What drug should be used with caution when tramadol is being given? (hint: think serotonin)

3. Buprenorphine is ___x more potent than morphine

4. GI effects of opioids

5. Which receptor is associated with the greatest degree of analgesia, and can be used for sedation as well as an appetite stimulant?

6. High risk of emesis in dogs and severe pruritus in horses when used as an epidural

7. Butorphanol is __x more potent than morphine

8. Which opioid is formulated in transdermal patches?

9. What opioid is excellent for sedation in young animals by itself and/or with benzos?

10. Coadministration with GABA agonists (benzos), alpha-2 agonists, and high dose phenothiazines lead to what relationship/effect?

11. Proper use of chronic oral opioids

12. Oral doses of butorphanol are 10x higher than ________ doses

13. Butorphanol is an antagonist at what receptor?

14. Oral transmucosal buprenorphine (not Simbadol) is used in what species?

15. the 3 opioid receptors

16. Tramadol is 1/10x as potent as morphine. What is the active metabolite of tramadol?

17. Two opioids with ceiling effects

18. Dose-dependent respiratory depression occurs through the activation of mu receptors. This causes a decreased response to

19. 4 mu agonists (moderate to severe pain)

20. Simbadol

21. What are the only two drugs with adequate oral bioavailability?

22. Duration of action for morphine. hydromorphone?

23. Hydromorphone is _____x more potent than morphine

24. Highest potential for dysphoria in dogs and hyperthermia in cats

25. Why does tramadol have a prolonged half-life in cats?

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