Genetic linkage is a phenomenon that describes the tendency of alleles that are close together on a chromosome to be inherited together. The closer two genes or DNA sequences are on a chromosome, the more likely they are to be inherited together. Genetic linkage analysis is a tool that can detect the location of disease genes on a chromosome. It's based on the observation that genes that are close together on a chromosome remain linked during meiosis. Genetic linkage analysis is a DNA indirect diagnosis method.
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