The major histocompatibility complex (MHC) is a large region of vertebrate DNA that contains genes that code for cell surface proteins. These proteins are essential for the adaptive immune system and are called MHC molecules. The MHC is a group of genes in animals and humans that encode cell surface markers, antigen-presenting molecules, and other proteins involved in immune function. In humans, the MHC is also known as the human leukocyte antigen (HLA) complex. The MHC is located on the short arm of chromosome 6 and contains the most polymorphic gene cluster of the entire human... Show more The major histocompatibility complex (MHC) is a large region of vertebrate DNA that contains genes that code for cell surface proteins. These proteins are essential for the adaptive immune system and are called MHC molecules. The MHC is a group of genes in animals and humans that encode cell surface markers, antigen-presenting molecules, and other proteins involved in immune function. In humans, the MHC is also known as the human leukocyte antigen (HLA) complex. The MHC is located on the short arm of chromosome 6 and contains the most polymorphic gene cluster of the entire human genome. The MHC is highly polymorphic from individual to individual. The MHC has three regions: MHC-I, MHC-II, and MHC-III. The classical HLA antigens encoded in each region include: MHC-I: HLA-A, -B, and -C MHC-II: HLA-DR, -DQ, and -DP MHC proteins are an important part of the vertebrate immune system. They help a body recognize a potential pathogen and mount an immune response. Show less
The major histocompatibility complex (MHC) is a large region of vertebrate DNA that contains genes that code for cell surface proteins. These proteins are essential for the adaptive immune system and are called MHC molecules.
The MHC is a group of genes in animals and humans that encode cell surface markers, antigen-presenting molecules, and other proteins involved in immune function. In humans, the MHC is also known as the human leukocyte antigen (HLA) complex. The MHC is located on the short arm of chromosome 6 and contains the most polymorphic gene cluster of the entire human genome. The MHC is highly polymorphic from individual to individual.
The MHC has three regions: MHC-I, MHC-II, and MHC-III.
The classical HLA antigens encoded in each region include: MHC-I: HLA-A, -B, and -C MHC-II: HLA-DR, -DQ, and -DP
MHC proteins are an important part of the vertebrate immune system. They help a body recognize a potential pathogen and mount an immune response.
Join 4M+ learners. Unlock unlimited quizzes, wrong-answer tracking, flashcards + reminders, study guides, and 1-on-1 challenges.