A high degree of precision in both the spatial arrangement of neurons and their connectivity is achieved from the outset, the wiring of some parts of the nervous system is later subject to activity-dependent refinement, such as the [...] of axons and the death of neurons

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1. A high degree of precision in both the spatial arrangement of neurons and their connectivity is achieved from the outset, the wiring of some parts of the nervous system is later subject to activity-dependent refinement, such as the [...] of axons and the death of neurons