Build - up of fat - cholesterol & calcium on inside of artery walls - Leads to hardening of walls with loss of elasticity or ability to expand fully - Plaque build up roughens walls so clotting factors can stick to walls - Plaque narrows lumen of art

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1. Build - up of fat - cholesterol & calcium on inside of artery walls - Leads to hardening of walls with loss of elasticity or ability to expand fully - Plaque build up roughens walls so clotting factors can stick to walls - Plaque narrows lumen of art