U.S. Route 66 also known as the Main Street of America or the Mother Road, was one of the original highways in the U.S. Highway System and was established in 1926 with a starting place in what major American city?

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1. U.S. Route 66 also known as the Main Street of America or the Mother Road, was one of the original highways in the U.S. Highway System and was established in 1926 with a starting place in what major American city?