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Monoclonal-gammopathy-of-uncertain-significance: What are the characteristics of mgus that distinguish it from myeloma?

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1. Monoclonal-gammopathy-of-uncertain-significance: What are the characteristics of mgus that distinguish it from myeloma?

Hyponaturaemia = plasma na less than 135 mmol/l causes of, pseudohyponaturaemia e.g hyperlipidemia hypoosmolar hyponaturaemia: 1. Primary na loss (secondary water gain), sweating, gi loss, renal loss 2. Primary water gain (secondary na loss) e.g siadh 3. Primary na gain (exceeded by secondary water gain) e.g hf, hepatic cirrhosis, nephrotic syndrome
1. Low concentration of paraprotein 2. Levels of other immunoglobulin are preserved 3. Paraprotein levels remain static rather than rising as in myeloma 4. Clinical features of myeloma such as bone pain, cytopenias, hypercalcaemia, and renal failure are not present 5. Less than 10% of plasma cells in the bone marrow
Intra-alveolar haemosiderin-laden macrophages seen in heart failure
Acute: chloramphenicol or fucithalmic ointment chronic: systemic tetracycline or a quinolone

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Monoclonal-gammopathy-of-uncertain-significance: What are the characteristics of mgus that distinguish it from myeloma?

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All trademarks, logos and brand names are the property of their respective owners. All company, product and service names used in this website are for identification purposes only. Use of these names, trademarks and brands does not imply endorsement.

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