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A 15 yo boy who recently immigrated from USA from Africa is brought to doctor by parents with fever and weight lsos. Exam shows hepatosplenomegaly and generalized lymphadenopathy. Lab shows WBC of 9000 Hb of 12.2 hematocrit of 35 %. Platelets of 125 000. Peripheral blood smear shows amastigotes in macrophages. 1. What is your diagnosis and why? 2. What cytokine is important for containing this infection?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 15 yo boy who recently immigrated from USA from Africa is brought to doctor by parents with fever and weight lsos. Exam shows hepatosplenomegaly and generalized lymphadenopathy. Lab shows WBC of 9000 Hb of 12.2 hematocrit of 35 %. Platelets of 125 000. Peripheral blood smear shows amastigotes in macrophages. 1. What is your diagnosis and why? 2. What cytokine is important for containing this infection?





 
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