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A 51 year old women comes to doctor for a routine examination. She is concerned about a recent history of abnormal periods, fatigue and weight loss. Pelvic examination shows a right adnexal mass. Resection of the mass confirms a malignant ovarian tumor. She reports a family history of breast cancer in her mother and aunt, both in their 40s. Her grandmother passed away from ovarian cancer. This patient likely has a genetic abnormality in a tumor suppressor gene on what chromosome?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 51 year old women comes to doctor for a routine examination. She is concerned about a recent history of abnormal periods, fatigue and weight loss. Pelvic examination shows a right adnexal mass. Resection of the mass confirms a malignant ovarian tumor. She reports a family history of breast cancer in her mother and aunt, both in their 40s. Her grandmother passed away from ovarian cancer. This patient likely has a genetic abnormality in a tumor suppressor gene on what chromosome?





 
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