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A 64 yo man comes to GP due to epigastric pain that is not relieved by antacids or PPI. He has recent unplanned weight loss. Patient reports that his sister had endometrial carcinoma before age 50. Father died of colorecetal cancer, as did his uncle. Physical exam reveals mild tenderness in epigastrium Upper endoscopy shows ulcerated mass on lesser curvature of stomach. Lower GI endoscopy is negative for polyps. 1. What condition is likely present in the family? 2. What is its inheritance? 3. How does it work?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 64 yo man comes to GP due to epigastric pain that is not relieved by antacids or PPI. He has recent unplanned weight loss. Patient reports that his sister had endometrial carcinoma before age 50. Father died of colorecetal cancer, as did his uncle. Physical exam reveals mild tenderness in epigastrium Upper endoscopy shows ulcerated mass on lesser curvature of stomach. Lower GI endoscopy is negative for polyps. 1. What condition is likely present in the family? 2. What is its inheritance? 3. How does it work?





 
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