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A 76 year old woman passes away after a prolonged hospital stay complicated by pneumonia. She has lung cancer with a history of smokin two packs of cigarettes a day for the last 45 years. Autopsy is performed and the cancerous lung is removed. Histologic exam shows the neoplasm consists of islands of mitoticaly active squamous cell carcinoma with central areas of coagulative necrosis. 1. Which of the following mechanisms most likely contributed to this type of necrosis. Why?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 76 year old woman passes away after a prolonged hospital stay complicated by pneumonia. She has lung cancer with a history of smokin two packs of cigarettes a day for the last 45 years. Autopsy is performed and the cancerous lung is removed. Histologic exam shows the neoplasm consists of islands of mitoticaly active squamous cell carcinoma with central areas of coagulative necrosis. 1. Which of the following mechanisms most likely contributed to this type of necrosis. Why?





 
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