An autopsy of an 83 year old man who died suddenly at a nursing home shows enlargement of heart and thickening of venricle walls. Histologic examination reveals presence of extracellular protein deposition. When stained with congo red and visualized under polarized light, protein shows apple green birefringence. Finding is not present in other ograns. His only medical problem was hypertension and tehre was no evidence of systemic ifnlammation. 1. Misfolidng of what protein most likely is responsible for autop[sy findings in this patient? 2. What condition did he have?

The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology