72 year old man comes to doctor because he is having progressive weakness of his legs and arms. He mentioned he had minor weakness in these muscles since childhood but his symptoms have recently worsened. He has no loss of sensation. vaccination history is unavailable. Vitals are normal. On physical exam you notice unprovoked fasiculations occuring in his muscles both upper and lower extremities. 1. What is a likely pathology he most likely has? 2. Briefly what is pathophys of this pathology? 3. What structures in the spinal cord are likely affected?

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1. 72 year old man comes to doctor because he is having progressive weakness of his legs and arms. He mentioned he had minor weakness in these muscles since childhood but his symptoms have recently worsened. He has no loss of sensation. vaccination history is unavailable. Vitals are normal. On physical exam you notice unprovoked fasiculations occuring in his muscles both upper and lower extremities. 1. What is a likely pathology he most likely has? 2. Briefly what is pathophys of this pathology? 3. What structures in the spinal cord are likely affected?