A 56 year old women comes to ICU for severe sepsis from a UTI. She has HX of DM. Next day she develops LOC, dyspnea and oliguria. Temp is 37.5 pusle 78 resp rate 18 BP 90/64 O2 sat at 90 %. She has purpura and ecchymoses over trunk/legs. She then develops anuria and dies on fifth day. 1. What condition has this lady developed secondary to sepsis? 2. What does this condition cause in the kidneys that can be found post mortem on renal biopsy? 3. What are complications of the above development?

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Use the mnemonic, A WET BED: A) maintenance of ACID-base balance; W) maintenance of WATER balance; E) balance of ELECTROLYTES; T) removal of TOXINS; B) control of BLOOD pressure; E) production of ERYTHROPOIETIN; and D) metabolism of vitamin D.


1. A 56 year old women comes to ICU for severe sepsis from a UTI. She has HX of DM. Next day she develops LOC, dyspnea and oliguria. Temp is 37.5 pusle 78 resp rate 18 BP 90/64 O2 sat at 90 %. She has purpura and ecchymoses over trunk/legs. She then develops anuria and dies on fifth day. 1. What condition has this lady developed secondary to sepsis? 2. What does this condition cause in the kidneys that can be found post mortem on renal biopsy? 3. What are complications of the above development?