A 72 year old women comes to ED by her sone with: -Periorbital edema -maculopapular rash on chest -Fever She has history of: -Hypertension -Diabetes -Osteoarthritis Labs show: -Na: 139 mEq/L -K 4.8 Cl: 100 Bicarb: 24 BUN: 52 Creatinine: 3.5 Urinalysis shows mild proteinuria and eosinophils. 1. What is the most likely diagnosis and what features suggest that? 2. What common drugs are known to cause acute interstial nephritis? 3. What is acute interstial nephritis? What sort of disease is it thought to be? 4. What potentiall complicaiton is a concern in AIN?

How do you remember renal physiology?
Use the mnemonic, A WET BED: A) maintenance of ACID-base balance; W) maintenance of WATER balance; E) balance of ELECTROLYTES; T) removal of TOXINS; B) control of BLOOD pressure; E) production of ERYTHROPOIETIN; and D) metabolism of vitamin D.