83 year old women comes to GP due to erythematous, itchy, ulcerating lesion of her left nipple associated with oozing, serosanguinous nipple discharge that has been present for the past month. She has tried over the counter topical creams but htey do no help. Biopsy specimen shows scattered large cells with clear, abundant cytoplasm located within the epidermis of the nipple. Immunohistochemical staining reveals these alrge celsl are positive for cytokeratin. 1. What is the likely pathology occuring?

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The development of the reproductive system begins with the formation of undifferentiated gonads and the paired mesonephric and paramesonephric ducts.


1. 83 year old women comes to GP due to erythematous, itchy, ulcerating lesion of her left nipple associated with oozing, serosanguinous nipple discharge that has been present for the past month. She has tried over the counter topical creams but htey do no help. Biopsy specimen shows scattered large cells with clear, abundant cytoplasm located within the epidermis of the nipple. Immunohistochemical staining reveals these alrge celsl are positive for cytokeratin. 1. What is the likely pathology occuring?