A 33 year old women comes to GP. She is healthy and has no current complaints. Has had two normal pregnancies. Last menstrual period was two weeks ago. Her mother died of breast cancer at 58 and her 40 year old sister was diagnosed with it a week ago. She is concerned with her family history. Lab studies show a genetic mutation that may be linked to breast cancer in her family. 1. What are the genes associated? 2. What does the mutation affect on the cellular level?

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The development of the reproductive system begins with the formation of undifferentiated gonads and the paired mesonephric and paramesonephric ducts.


1. A 33 year old women comes to GP. She is healthy and has no current complaints. Has had two normal pregnancies. Last menstrual period was two weeks ago. Her mother died of breast cancer at 58 and her 40 year old sister was diagnosed with it a week ago. She is concerned with her family history. Lab studies show a genetic mutation that may be linked to breast cancer in her family. 1. What are the genes associated? 2. What does the mutation affect on the cellular level?