An 8-year-old black-and-tan coonhound presents for lethargy, depression, and subcutaneous edema. His PCV is 45%, BUN 8.5 mg/dl, Cr 1.0 mg/dl, TP 3.3 g/dl, albumin 1.3 g/dl, ALT 200 U/L, AST 100 U/L, Alk Phos 250 U/L, GGT 20 IU/L, cholesterol 116 mg/dl, calcium 10 mg/dl, phosphorus 5 mg/dl, sodium 150 mg/dl, potassium 5 mg/dl, chloride 100 mEq/L, bicarbonate 14 mEq/L (low). Urinalysis shows 2+ bilirubin and a specific gravity of 1.012. The edema is due to

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An 8-year-old black-and-tan coonhound presents for lethargy, depression, and subcutaneous edema. His PCV is 45%, BUN 8.5 mg/dl, Cr 1.0 mg/dl, TP 3.3 g/dl, albumin 1.3 g/dl, ALT 200 U/L, AST 100 U/L, Alk Phos 250 U/L, GGT 20 IU/L, cholesterol 116 mg/dl, calcium 10 mg/dl, phosphorus 5 mg/dl, sodium 150 mg/dl, potassium 5 mg/dl, chloride 100 mEq/L, bicarbonate 14 mEq/L (low). Urinalysis shows 2+ bilirubin and a specific gravity of 1.012. The edema is due to