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Basic Biology Practice Test: The Molecular Basis of Inheritance
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Related Test: Basic Biology Practice Test: The Chromosomal Basis of Inheritance

Basic Biology Practice Test: The Molecular Basis of Inheritance
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25 Questions

1. What is meant by the description 'antiparallel' regarding the strands that make up DNA ?
2. Which of the following help(s) to hold the DNA strands apart while they are being replicated?
3. What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?
4. The leading and the lagging strands differ in that
5. What is the function of topoisomerase?
6. In analyzing the number of different bases in a DNA sample, which result would be consistent with the base-pairing rules?
7. Eukaryotic telomeres replicate differently than the rest of the chromosome. This is a consequence of which of the following?
8. To repair a thymine dimer by nucleotide excision repair, in which order do the necessary enzymes act?
9. In E.coli, there is a mutation in a gene called dnaB that alters the helicase that normally acts at the origin. Which of the following would you expect as a result of this mutation?
10. In an analysis of the nucleotide composition of DNA , which of the following will be found?
11. The DNA of telomeres has been found to be highly conserved throughout the evolution of eukaryotes. What does this most probably reflect?
12. After mixing a heat-killed, phosphorescent strain of bacteria with a living nonphosphorescent strain, you discover that some of the living cells are now phosphorescent. Which observations would provide the best evidence that the ability to fluoresce is a heritable trait?
13. Studies of nucleosomes have shown that histones (except H1) exist in each nucleosome as two kinds of tetramers: one of 2 H2A molecules and 2 H2B molecules, and the other as 2 H3 and 2 H4 molecules. Which of the following is supported by this data?
14. The elongation of the leading strand during DNA synthesis
15. Which of the following represents the order of increasingly higher levels of organization of chromatin?
16. Suppose you are provided with an actively dividing culture of E.coli bacteria to which radioactive thymine has been added. What would happen if a cell replicates once in the presence of this radioactive base?
17. The spontaneous loss of amino groups from adenine in DNA results in hypoxanthine, an uncommon base, opposite thymine. What combination of proteins could repair such damage?
18. It became apparent to Watson and Crick after completion of their model that the DNA molecule could carry a vast amount of hereditary information in which of the following?
19. Which of the following sets of materials are required by both eukaryotes and prokaryotes for replication?
20. A biochemist isolates, purifies, and combines in a test tube a variety of molecules needed for DNA replication. When she adds some DNA to the mixture, replication occurs, but each DNA molecule consists of a normal strand paired with numerous segments of DNA a few hundred nucleotides long. What has she probably left out of the mixture?
21. The enzyme telomerase solves the problem of replication at the ends of linear chromosomes by which method?
22. Which enzyme catalyzes the elongation of a DNA strand in the 5' → 3' direction?
23. At a specific area of a chromosome, the sequence of nucleotides below is present where the chain opens to form a replication fork:
3' C C T A G G C T G C A A T C C 5'
An RNA primer is formed starting at the underlined T (T) of the template. Which of the following represents the primer sequence?
24. Which of the following statements is true of histones?
25. If a cell were unable to produce histone proteins, which of the following would be a likely effect?

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