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___________ causes vasoconstriction which increases afterload, blood pressure and contributes to the worsening of left ventricular hypertrophy, dilation and worsening contraction. _______________ also has direct toxic effects on the myocytes and contributes to sarcomere death, loss of normal collagen and the development of interstitial fibrosis.

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1. ___________ causes vasoconstriction which increases afterload, blood pressure and contributes to the worsening of left ventricular hypertrophy, dilation and worsening contraction. _______________ also has direct toxic effects on the myocytes and contributes to sarcomere death, loss of normal collagen and the development of interstitial fibrosis.





 
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