Is defined as an abnormal level of lipoproteins. This results from genetics or poor diet. Genetic issues which cause ___________ result in an abnormal lipid metabolism and elevated levels. Secondary causes of ______________ include diabetes, hypothyroidism, pancreatitis, renal nephrosis, the use of thiazide diuretics, beta blockers, glucocorticoids, interferons, and antiretroviral agents. Increased levels of LDL are associated with an increased risk of the development of CAD. HDLs are responsible for returning fat to the liver. Low levels are an indicator of increased coronary events.