Results from atherosclerotic changes which affect the extremities. This most commonly affects the arteries of the lower extremities. It is associated with significant morbidity and mortality. The incidence increases with age and is more common in African Americans

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1. Results from atherosclerotic changes which affect the extremities. This most commonly affects the arteries of the lower extremities. It is associated with significant morbidity and mortality. The incidence increases with age and is more common in African Americans