The extracellular matrix (ECM) provides structural support to cells and tissues. It also generates cell signals that affect cell proliferation, differentiation, migration, and adhesion. ECM-cell interactions are mediated by cell surface receptors, either directly or indirectly with cooperative molecules. The ECM is also constantly remodeling, which influences cell-signaling pathways. ECM-cell interactions play a crucial role in: Embryonic development Differentiation Tissue remodeling Diseases like fibrosis and cancer Dysregulated signaling between the ECM and cells can lead to... Show more The extracellular matrix (ECM) provides structural support to cells and tissues. It also generates cell signals that affect cell proliferation, differentiation, migration, and adhesion. ECM-cell interactions are mediated by cell surface receptors, either directly or indirectly with cooperative molecules. The ECM is also constantly remodeling, which influences cell-signaling pathways. ECM-cell interactions play a crucial role in: Embryonic development Differentiation Tissue remodeling Diseases like fibrosis and cancer Dysregulated signaling between the ECM and cells can lead to different diseases. Topics include: Cells Interaction - Integrins, Cells Interaction, Immunoglobulin Superfamily, Adherens Junctions, Tight Junctions, Gap Junctions, & Cell Walls. Show less
The extracellular matrix (ECM) provides structural support to cells and tissues. It also generates cell signals that affect cell proliferation, differentiation, migration, and adhesion. ECM-cell interactions are mediated by cell surface receptors, either directly or indirectly with cooperative molecules. The ECM is also constantly remodeling, which influences cell-signaling pathways.
ECM-cell interactions play a crucial role in: Embryonic development Differentiation Tissue remodeling Diseases like fibrosis and cancer Dysregulated signaling between the ECM and cells can lead to different diseases.
Topics include: Cells Interaction - Integrins, Cells Interaction, Immunoglobulin Superfamily, Adherens Junctions, Tight Junctions, Gap Junctions, & Cell Walls.
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