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CHEM204 Final Exam - Bioorganic Chemistry
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MCQS on the biological importance of organic molecules. Topics include bioorganic mechanisms, chirality, lipids, carbohydrates, animo acids, peptides, proteins, nucleic acids, enzymes, coenzymes, and coupled reactions, and lipid, carbohydrate, amino acid, and nucleotide metabolism.

CHEM204 Final Exam - Bioorganic Chemistry
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25 Questions

1. What is the biological function of the following pathway?

2. Fill in the blank.  High ammonia levels _______.
3. Glyceraldehyde-3-phosphate (G3P) is an intermediate of glycolysis. The formula of G3P is shown below. G3P is converted to the next intermediate in a redox reaction catalyzed by a dehydrogenase enzyme. What is the product of this reaction?

A.

B.

C.

D.

4. The most common genetically inherited SCID affects the enzyme adenosine deaminase. This deficiency results in which of the following?
5. Use the following structural formula to calculate the oxidation state number of the carbon atom in urea.

6. Fill in the blanks. ___________ is synthesized from glutamine for pyrimidine biosynthesis, but for amino acid catabolism, it is derived from ____________ bicarbonate.
7. Fill in the blanks. Glutamine, aspartate, and _________ are building blocks of __________ base synthesis.
8. Which of the following structural formula show an α, and which one shows a β anomer?
1. 2.
9. Fill in the blank.  The diagram of protein synthesis can be seen below. The addition of new amino acids during protein synthesis is a(n) _____ reaction.
10. Fill in the blank.  Both ATP and citric acid are allosteric inhibitors of the phosphofructokinase enzyme. High levels of these compounds indicate that ________________. 
11. The following diagram depicts energy level changes during chemical reactions. One of the lines represents a reaction without a catalyst. Could the other line be the energy profile of an enzyme catalyzed reaction?

12. Fill in the blanks. ___________ the end product of β-oxidation, which contributes to ___________ in the first step of the Szent-Györgyi-Krebs cycle. An increased level of the latter activates fatty acid synthesis through the activation of acetyl-CoA carboxylase.
13. Which metabolic pathway has the intermediate which is used to start the biosynthesis of all branch chain amino acids?
14. Fill in the blank. Bile acid can emulsify fats, because it is _____.
15. Which metabolic pathway has the intermediate which is used to start the biosynthesis of threonine and glutamate?
16. Which nucleotides are used as energy source by the cell?
17. Why are BRCAs not synthesized in human tissues?
18. Fill in the blank. The rearrangements that result in the common cyclic forms of D-glucose can be seen below. The cyclic form is a(n) ______.
19. Which metabolic pathway has the intermediate which is used to start the biosynthesis of histidine?
20. Fill in the blank. Triglycerides ______ chiral carbon atoms.
21. Sucrose, the common table sugar, is a disaccharide, which is formed from glucose and fructose monosaccharides. The structural formula of sucrose is shown below. The formation of sucrose from glucose and fructose is a(n) _____ reaction.
22. What regulates the committed step of the urea cycle? 
23. Which of the following reactions produces mevalonate?
A.

B.

C.

D.
24. How many chiral carbon atoms can be found in the following organic molecule?
25. Which metabolite is involved in both the salvage of adenine and the biosynthesis of adenosine-5'-monophosphate?

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