In response to attack by a pathogen or allergen - basophils and mast cells around the body release large amounts of which of the following substances - which is responsible for dilating walls of blood vessels and making capillaries leaky?

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In response to attack by a pathogen or allergen - basophils and mast cells around the body release large amounts of which of the following substances - which is responsible for dilating walls of blood vessels and making capillaries leaky?